Dr CHERIF Mahamoud Sama MD, PhD,


Clinical Research Manager

Email : mahamoud-sama.cherif@master-microbio.com 

Tel : +224 628889797


Biographie

Médecin pédiatre, attaché de recherche à la FSTS de l’Université Gamal Abdel Nasser de Conakry et chargé de recherche clinique au Centre National de formation et de Recherche en santé Rurale de Maferinyah.

Langue parlée : le français, l’anglais et le japonais de base.

J’ai un doctorat d’état en médecine et un DES en pédiatrie de l’Université Gamal Abdel Nasser de Conakry et un PhD en Science Médical à L’université de Nagasaki, Japon.

J’ai acquis des compétences en bactériologie, virologie, immunologie et développement préclinique de vaccins à ADN et à base de protéines de synthèse et je maîtrise les techniques moléculaires (PCR, séquençage Western blot) et immunologiques (Elisa, cytométrie en flux, Elispot,) et en expérimentations animales.


  • La liste des publications
  1. Elevated IL-17 levels in semi-immune anaemic mice infected with Plasmodium berghei ANKA..Malar J. 2018 Apr 17;17(1):169. doi: 10.1186/s12936-018-2257-x.PMID: 29665817 
  2. Deployment of a Reverse Transcription Loop-Mediated Isothermal Amplification Test for Ebola Virus Surveillance in Remote Areas in Guinea. J Infect Dis. 2016 Oct 15;214(suppl 3):S229-S233. doi: 10.1093/infdis/jiw255.
  3. Dengue Virus Serotypes 1 and 2 Responsible for Major Dengue Outbreaks in Nepal: Clinical, Laboratory, and Epidemiological Features. Am J Trop Med Hyg. 2017 Oct;97(4):1062-1069. doi: 10.4269/ajtmh.17-0221.PMID: 29031282 
  4. Development and Evaluation of Reverse Transcription-Loop-Mediated Isothermal Amplification (RT-LAMP) Assay Coupled with a Portable Device for Rapid Diagnosis of Ebola Virus Disease in Guinea. PLoS Negl Trop Dis. 2016 Feb 22;10(2):e0004472. doi: 10.1371/journal.pntd.0004472.
  5. Immunogenicity and anti-fecundity effect of nanoparticle coated glutathione S-transferase (SjGST) DNA vaccine against murine Schistosoma japonicum infection. Parasitol Int. 2015 Aug;64(4):24-31. doi: 10.1016/j.parint.2015.01.005.
  6. The predictor of mortality outcome in adult patients with Ebola virus disease during the 2014-2015 outbreak in Guinea. Eur J Clin Microbiol Infect Dis. 2017 Apr;36(4):689-695. doi: 10.1007/s10096-016-2850-2
  7. Characterization of a gene family encoding SEA (sea-urchin sperm protein, enterokinase and agrin)-domain proteins with lectin-like and heme-binding properties from Schistosoma japonicum. PLoS Negl Trop Dis. 2014 Jan 9;8(1):e2644. doi: 10.1371/journal.pntd.0002644. eCollection 2014.PMID: 24416467 
  8. Nanoparticle formulation enhanced protective immunity provoked by PYGPI8p-transamidase related protein (PyTAM) DNA vaccine in Plasmodium yoelii malaria model. Vaccine. 2014 Apr 7;32(17):1998-2006. doi: 10.1016/j.vaccine.2014.01.005.
  9. Effect of nanoparticle coating on the immunogenicity of plasmid DNA vaccine encoding P. yoelii MSP-1 C-terminal..Vaccine. 2011 Apr 12;29(17):3239-47. doi: 10.1016/j.vaccine.2011.02.033. Epub 2011 Feb 26.PMID: 21354479
  10. Anti-erythropoietin antibody levels and its association with anaemia in different strains of semi-immune mice infected with Plasmodium berghei ANKA. Malar J. 2013 Aug 27;12:296. doi: 10.1186/1475-2875-12-296.PMID: 23978045 
  11. Immunogenicity of novel nanoparticle-coated MSP-1 C-terminus malaria DNA vaccine using different routes of administration. Vaccine. 2011 Nov 8;29(48):9038-50. doi: 10.1016/j.vaccine.2011.09.031.
  12. Selection and identification of malaria vaccine target molecule using bioinformatics and DNA vaccination. Vaccine. 2010 Oct 4;28(42):6868-75. doi: 10.1016/j.vaccine.2010.08.019. Epub 2010 Aug 13.PMID: 20709002

Etudes cliniques:

  1. Prognostic and Predictive Factors of Ebola Virus Disease Outcome in Elderly People during the 2014 Outbreak in Guinea..Am J Trop Med Hyg. 2018 Jan;98(1):198-202. doi: 10.4269/ajtmh.17-0372. Epub 2018 Jan 1.PMID: 29141743 
  1. Morbidity and mortality outcomes in neonates who were transferred from home and hospitals to the only neonatal intensive care unit in Guinea: a descriptive report using routinely collected health data. Int Health. 2019 Nov 13;11(6):455-462. doi: 10.1093/inthealth/ihz001.PMID: 30753463
  1. Ebola virus disease in children during the 2014-2015 epidemic in Guinea: a nationwide cohort study. Eur J Pediatr. 2017 Jun;176(6):791-796. doi: 10.1007/s00431-017-2914-z. Epub 2017 Apr 25.PMID: 28444452 .
  1. Modifiable predictors of severe heart failure in Morocco: a descriptive study using routinely collected health data. Pan Afr Med J. 2019 Sep 3;34:6. doi: 10.11604/pamj.2019.34.6.17998. eCollection 2019.PMID: 31762875